Search results for "molecular surveillance"

showing 7 items of 7 documents

Surveillance Data for Eight Consecutive Influenza Seasons in Sicily, Italy

2019

Influenza A and B outbreaks occur each year with different activity and molecular patterns. To date, knowledge of seasonal epidemiology remains a prerequisite not only to put in place the most effective immunization strategy against influenza but also to identify population groups at higher risk of developing serious complications. A retrospective analysis of influenza surveillance data from 2010 to 2018 aimed to explore the epidemiology of influenza in Sicily, at the primary care and hospital level. Overall, 6,740 patients with acute respiratory infection were tested, of which 3,032 (45.0%) were positive for influenza. The relative proportion of type A and B viruses markedly varied across …

MalePediatricsCommunityDiseaseSettore MED/42 - Igiene Generale E ApplicataSeverity of Illness IndexDisease Outbreakslaw.inventionRisk FactorslawEpidemiologyChildRespiratory Tract InfectionsSicilyeducation.field_of_studyVaccinationRespiratory infectionArticlesMiddle AgedIntensive care unitHospitalizationIntensive Care UnitsInfectious DiseasesMolecular surveillanceInfluenza A virusChild PreschoolEpidemiological MonitoringFemaleSeasonsAdultmedicine.medical_specialtyAdolescentPopulationYoung AdultVirologyInfluenza HumanmedicineHumanseducationAgedRetrospective Studiesbusiness.industryInfantOutbreakmedicine.diseaseObesityInfluenzaInfluenza B virusImmunizationParasitologyRisk factorbusinessThe American Journal of Tropical Medicine and Hygiene

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Genomic analysis and lineage identification of SARS-CoV-2 strains isolated from migrants travelling through the Libyan route

2021

Many African countries, representing the origin of the majority of refugees, asylum-seekers, and other migrants, toward regions bordering on the Mediterranean area, are experiencing sustained local transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Sicily is one of the main entry gates of migrants crossing into Europe. We conducted a pilot study, based on the full-genome sequencing of SARS-CoV-2 strains isolated from migrants coming to Sicily by crossing the Mediterranean Sea, with the aim to investigate the viral genome polymorphism and to describe their genetic variations and the phylogenetic relationships. On June 21, a nongovernmental organization vessel rescu…

SARS-CoV-2 molecular surveillance migrant asylum-seeker Mediterranean Sea NGSSettore MED/42 - Igiene Generale E Applicata

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Genomic Analysis and Lineage Identification of SARS-CoV-2 Strains in Migrants Accessing Europe Through the Libyan Route

2021

0106 biological sciencesLineage (genetic)virusesPilot ProjectsGenomicsLibyaasylum-seeker010603 evolutionary biology01 natural scienceslaw.invention03 medical and health sciencesMediterranean seaPhylogeneticslawMediterranean SeaHumansGenetic variabilitySicilyPhylogeny030304 developmental biologyTransients and Migrants0303 health sciencesPhylogenetic treeSARS-CoV-2lcsh:Public aspects of medicinefungiPublic Health Environmental and Occupational HealthCOVID-19virus diseaseslcsh:RA1-1270Genomicsmolecular surveillanceBrief Research Reportlanguage.human_languageEuropemigrantGeographyTransmission (mechanics)Evolutionary biologyNGSAfricalanguagePublic HealthSicilianFrontiers in Public Health

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First detection of SARS-CoV-2 A.23.1 sub-lineage in migrants arriving to Italy via the Mediterranean Sea and public health implications

2021

COVID-19 Mediterranean sea Migrants Molecular surveillance NGS Phylogeny analysis Public health SARS-CoV-2 Vaccination programs2019-20 coronavirus outbreakmedicine.medical_specialtyLineage (genetic)Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Vaccination programsMigrantsArticlePhylogeny analysisMediterranean seamedicineHumansPhylogenyTransients and MigrantsPublic healthSARS-CoV-2Public healthPublic Health Environmental and Occupational HealthCOVID-19VirologyInfectious DiseasesGeographyItalyMolecular surveillanceNGSMediterranean seaTravel Medicine and Infectious Disease

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COVID-19 emergency in Sicily and intersection with the 2019-2020 influenza epidemic.

2021

SARS-CoV-2 Influenza Molecular surveillance ItalySicilySettore MED/42 - Igiene Generale E Applicata

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Molecular surveillance of pandemic influenza A(H1N1) viruses circulating in Italy from May 2009 to February 2010: association between haemagglutinin …

2010

Haemagglutinin sequences of pandemic influenza A(H1N1) viruses circulating in Italy were examined, focusing on amino acid changes at position 222 because of its suggested pathogenic relevance. Among 169 patients, the D222G substitution was detected in three of 52 (5.8%) severe cases and in one of 117 (0.9%) mild cases, whereas the D222E mutation was more frequent and evenly distributed in mild (31.6%) and severe cases (38.4%). A cluster of D222E viruses among school children confirms reported human-to-human transmission of viruses mutated at amino acid position 222.

MaleMolecular surveillance; Pandemic influenza A(H1N1); Haemagglutinin mutations; Italy from May 2009 to February 2010pandemic influenzasurveillance of pandemic influenza A(H1N1); Molecular surveillance; pandemic influenzaEpidemiologyvirusesHaemagglutinin mutationssurveillance of pandemic influenza A(H1N1)Settore MED/42 - Igiene Generale E Applicatamedicine.disease_causeSeverity of Illness IndexInfluenza A Virus H1N1 SubtypePandemic influenza A(H1N1)PandemicInfluenza A VirusA(H1N1)ChildMutationReverse Transcriptase Polymerase Chain ReactionTransmission (medicine)Adolescent; Adult; Age Distribution; Aged; Amino Acid Substitution; Child; Child Preschool; Female; Hemagglutinins; Humans; Infant; Influenza A Virus H1N1 Subtype; Influenza Human; Italy; Male; Middle Aged; Mutation; Population Surveillance; Reverse Transcriptase Polymerase Chain Reaction; Severity of Illness Index; Sex Distribution; Young Adult; PandemicsMiddle AgedItaly from May 2009 to February 2010Molecular surveillance; pandemic influenza; A(H1N1); Italy; haemagglutinin mutationsHemagglutininsMolecular surveillanceItalyChild PreschoolPopulation SurveillanceFemaleHumanAdultAdolescentBiologyDisease clusterDisease courseYoung AdultAge DistributionVirologyInfluenza HumanmedicineHumansH1N1 SubtypeSex DistributionPreschoolhaemagglutinin mutationsPandemicsAgedMolecular epidemiologyPublic Health Environmental and Occupational HealthPandemic influenzaInfantVirologyInfluenzaMutational analysisAmino Acid SubstitutionMutationEurosurveillance

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Respiratory Syncytial Virus: New Challenges for Molecular Epidemiology Surveillance and Vaccination Strategy in Patients with ILI/SARI.

2021

Several respiratory pathogens are responsible for influenza-like illness (ILI) and severe respiratory infections (SARI), among which human respiratory syncytial virus (hRSV) represents one of the most common aetiologies. We analysed the hRSV prevalence among subjects with ILI or SARI during the five influenza seasons before the emergence of SARS-CoV-2 epidemic in Sicily (Italy). Respiratory specimens from ILI outpatients and SARI inpatients were collected in the framework of the Italian Network for the Influenza Surveillance and molecularly tested for hRSV-A and hRSV-B. Overall, 8.1% of patients resulted positive for hRSV. Prevalence peaked in the age-groups &lt

medicine.medical_specialtyrespiratory syncytial virusImmunologySettore MED/42 - Igiene Generale E ApplicataVirusArticleInternal medicineDrug DiscoveryEpidemiologymedicinerisk factorsPharmacology (medical)In patientRespiratory systemPharmacologyMolecular epidemiologybusiness.industryPublic healthRvirus diseasesmolecular surveillancevaccinationrespiratory tract diseasesVaccinationInfectious Diseasesrisk factorEtiologyMedicinecommunityrespiratory syncytial virubusinesshospitalizationVaccines

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